Nils Andreas Boe (September 10, 1913–July 30, 1992) was an American politician who served as the Republican Governor of South Dakota from 1965 to 1969.

Boe was born in Baltic in Minnehaha County, South Dakota and served in the state legislature representing Sioux Falls from 1953 to 1958. He was Lieutenant Governor from 1963 to 1965 and Governor from 1965 to 1969. He is best known for improving the state's reservoir system.