James Moore is the name of more than one person of note:

• James Moore , colonial governor of South Carolina from 1700-03 and 1719-21.
• James Moore , an 18th century glass maker and cabinet maker, employed as clerk of works on the building of Blenheim Palace.
• James Moore (1850- ?), an cycling racer.
• Slim Harpo (1924-1970), a blues musician whose real name was James Moore.
• James Moore (1976- ), a Canadian politician.