Chauvenet's Criterion is a means of assessing whether one piece of experimental data — an outlier — from a set of observations, is spurious.
To apply Chauvenet's Criterion, first calculate the mean and standard deviation. Based on how much the suspect datum differs from the mean, use the normal distribution function (or a table thereof) to determine the probability that a given data point will be at the value of the suspect data point. Multiply this probability by the number of data points taken. If the result is less than .5, the suspicious data point may be discarded.
For instance, suppose a value is measured experimentally in several trials as 9, 10, 10, 10, 11, and 50. The mean is 16.7 and the standard deviation 16.3. 50 differs by 16.7 by 33.3, slightly more than two standard deviations. The probability of taking data more than two standard deviations from the mean is roughly .05. Six measurements were taken, so the probability that one should be so far from the mean is .05*6 = .3. Because .3 < .5, according to Chauvenet's Criterion, the measurement of 50 should be discarded (leaving a new mean of 10, with standard deviation .7).
References
Taylor, John R. An Introduction to Error Analysis. 2nd edition. Sausolito, California: University Science Books, 1997. pp 166-8.