CS, Cs or cs may stand for:

• the chemical element Caesium (Cs)
• Christian Science
• Clinical Skills examination for step II of the USMLE
• comprehensive school
• Computer science
• Conservative Shithead, a song by Napalm Death that is abbreviated to CS
• Cursed Soul, a weapon in the MMORPG Neocron
• Counter-Strike, the computer game
• Credit Suisse
• CS gas
• Czech language (ISO 639 alpha-2, cs)
• Serbia and Montenegro (ISO 3166-1 2-letter country abbreviation, from Crna gora i Srbija)
• Central Station; however, in the Netherlands names like Amsterdam CS have been changed into Amsterdam Centraal.
• US Navy hull classification symbol for Scout Cruisers
• Cockayne syndrome
• Cowden syndrome
• Creative Suite, the newest set of products from Adobe Systems Incorporated, including the popular Adobe Photoshop CS.
• Customer Service
• Cybersex
• the IATA code for Continental Micronesia
• Crystal Space